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Diagnostic Antimicrobial Agents: Introduction, Working Mechanism and Uses
Diagnostic antimicrobial agents(Antibiotics) There are some diagnostic antimicrobial agents that are used for the presumptive identification of various organisms. They are the most common optochin, bacitracin( 10 µg), bacitracin (0.04µg), and novobiocin. The most common antimicrobial agents and their uses: Optochin (ethylhydrocupreine hydrochloride)-5µg: Mode of action: Optochin is a quinine derivative. It selectively inhibits the growth of S. pneumoniae at very low concentrations i.e. 5 mg/mL or even less. It may also inhibit viridans streptococci, but requires higher concentrations....
BD BACTEC Blood culture system: Introduction, Principle and Processing
BD BACTEC Blood Culture System Introduction BD BACTEC Blood Culture System Conventional blood culture Vs BD Bactec Blood culture is used to detect blood-borne pathogens essential in identifying bacteria responsible for bacteremia and sepsis. Nowadays, Several automated blood culture systems are available commercially. The advantages of all those such systems are the elimination of the need for blind subculture and the shortening of the usual incubation period of five to seven days. It also minimizes contamination and...
Sodium hypochlorite: Introduction, Preparation and Uses
Introduction of Sodium hypochlorite Sodium hypochlorite (NaOCl) in solution exhibits broad-spectrum anti-microbial ( bacteria, virus, fungi, and parasites) activity and is widely used in healthcare facilities in a variety of settings. It is usually diluted in water depending on its intended use. "Strong chlorine solution" is a 0.5% solution of hypochlorite (containing approximately 5000 ppm free chlorine) used for disinfecting areas contaminated with body fluids, including large blood spills (the area is first cleaned with detergent...