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Histoplasma capsulatum was discovered by Pathologist, Samuel Taylor Darling in 1906. It is a causative agent of histoplasmosis ( systemic disease) sometimes called Darling’s disease, in honor of discoverer. It a domorphic fungus and thus it grows as filamentous molds as saprobes and in culture at 25°C; while in humans or culture at 37 °C , it transforms to a unicellular morphology ( yeast cells — Histoplasma : Introduction, Morphology,Life Cycle, Pathogenesis, Laboratory Diagnosis, Treatment and Prevention
Introduction of Histoplasma capsulatum Histoplasma capsulatum was discovered by Pathologist, Samuel Taylor...

Mycoplasma: A cell wall deficient organism was isolated by Nocard and Roux in 1998, from a cattle suffering from pleuropneumonia. The organism was filterable through bacteria stopping filter and highly pleomorphic. Because of their resemblance to the organisms responsible for pneumonia in the cattle, for the many years this organism was called Pleuropneumonia like organism (PPLO). Since organism are seen like fungus in the form of branching filaments, the name given today for this organism is Mycoplasma — Mycoplasma: Introduction, Characteristics, Pathogenecity, Lab Diagnosis and Treatment
Introduction of Mycoplasma A cell wall deficient organism was isolated by Nocard...

Chalmydiae are non - motile, gram- negative obligate intracellular bacteria. They contains both RNA and DNA. They multiply within the cytoplasm of host cells, which form characteristic intracellular inclusion bodies. They can be seen with light microscope after staining with Giemsa stain better with Castaneda, Machiavello or Giminez stains. They contain better with Castaneda, Machiavello or Giminez stains. They contain glycogen matrix. They cal also be demonstrated yb Immunofluorescence tets. The cell wall structure of Chalmydiae is close to Gram - negative bacteria. They are susceptible to Tetracycline. They have restricted metabolic activities. None of these metabolic reaction can synthesize the energy . Therefore , they have been considered as energy parasite that they use the ATP produced by the host cells for their own requirements. — Chalmydiae: Introduction, Morphology,Life Cycle,Pathogenecity, Lab Diagnosis and Treatment
Introduction of Chlamydiae Chlamydiae are non - motile, gram-negative obligate intracellular bacteria....

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