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2DG Drug to Treat Covid-19: Introduction, Mode of Action, Availability, Dosage, Price, Merit and Demerits
Introduction of 2DG drug 2DG Stands for 2-deoxy-D-glucose and it is a glucose analogue, that looks like glucose but is not since 2-deoxy-D-glucose changes into 2-deoxy-D-glucose- 6-phosphate by the enzyme, hexokinase and is not further utilized due to acting as inhibitors of other enzymes of the glycolysis pathway. This is the reason, energy is not created. It is also applicable for treating tumours, and cancer cells. This 2DG inhibits SARS-CoV-2 multiplication and thus there will not be a...
Antigen, Antibody and PCR Tests in COVID-19: Introduction, Importance, Applications and Demerits
Introduction of Antigen, Antibody and PCR Tests in COVID-19 Antigen, antibody, and PCR tests in COVID-19 patients are the most common assays applicable for laboratory diagnosis of COVID-19. Anigen is a foreign substance that induces an immune response. The nucleocapsid (N) is the most common antigen for the SRAS-CoV-2 antigen test and is also called antigen-detecting rapid diagnostic tests (Ag-RDTs). It works in the principle of immunochromatographic (lateral flow) assay. Ag-RDTs for COVID-19 will most often be positive when...
Mucormycosis/Black Fungus Disease in COVID Patients: Introduction, Causative agent, Sign and symptoms, Lab Diagnosis, Treatment, Prevention and Control
Introduction of Mucormycosis/Black Fungus Disease Mucormycosis/black fungus disease (previous zygomycosis) is a fungal infection that principally affects people who are immunocompromised or on medication for other health problems that reduce their ability to fight environmental pathogens. It may be suspected in COVID-19 patients, diabetics, or immunosuppressed individuals having the following conditions- Sinusitis – nasal blockage or congestion, nasal discharge (blackish/bloody), local pain on the cheekbone One-sided facial pain, numbness, or swelling Blackish discoloration over the bridge of nose/palate...