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Simulated Respiratory Secretion (SRS): Introduction, Application, Advantage and Disadvantage
Introduction of Simulated Respiratory Secretion The simulated respiratory secretion brief form is SRS. It is a matrix that acts as a surrogate for clinical samples. SRS is beneficial due to having following reasons- Clinical samples can be difficult to obtain. It may deteriorate over time. It is also inconsistent in composition. SRS is very common nowadays for monitoring the validity of analytical testing related to the Influenza virus and also in SARS-CoV-2. Its composition is well maintained with...
Hematoxylin and Eosin Stain: Introduction, Principle, Procedure, Result Interpretation and Keynotes
Introduction of Hematoxylin and Eosin Stain Hematoxylin and eosin stain is also called H&E in short. It is one of the principal tissue stains used in histopathology to find out cancer from a suspected biopsy. The stain was first introduced by A. Wissowzky in 1876. The cell nuclei are stained blue and the cytoplasm and extracellular matrix are stained pink Principle of Hematoxylin and Eosin Stain Hematoxylin and eosin (H&E) are the principal stains applied for the demonstration...
Indirect Coomb Test (ICT): Introduction, Principle, Procedure, Result Interpretation and Clinical Significance
Introduction of Indirect Coomb Test (ICT) The indirect Coomb Test is a type of Coomb’s test also called the anti-globulin test. It is of two types-Direct Coomb’s test (DCT) and the Indirect Coomb’s test (ICT). DCT uses to detect sensitized red blood cells (RBCs) while ICT detects the presence of ‘incomplete’ Rh antibodies i.e. IgG antibodies. IgG antibodies are capable of sensitizing RBCs but incapable of causing agglutination of RBCs (hemagglutination). Coomb’s test was introduced by...